September 27, 2022

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Your Questions, Our Answers | When the booster dose is not “third”

Even one, two, three, four dose vaccines, one or two infections, how many antibodies will be needed to deal with the fifth wave? A look at some of the special events waiting for the booster dose.

Released at 5:00 p.m.

Judith Laczabelle

Judith Laczabelle

“If I got my third dose three months ago, should I get a booster dose this winter? ⁇

This is the position of some readers, such as Mario Saint-Pierre. “My first dose was the astrogenic vaccine. Second, Pfizer. I got the second dose of the Pfizer vaccine three months ago because I had to travel. Am I supposed to have three doses? ⁇

This is called a “third dose” because it is the third dose for most vaccines. But really, its official name is “booster dose”. And, yes, Mr. The Ministry of Health and Social Services (MSSS) confirms that St-Pierre, like all other individuals, had been on the last dose for more than three months and was eligible for the booster dose.

According to its latest comment, Quebec’s immunization team allows these individuals to receive a “fourth dose”, although there are still uncertainties about the benefits and risks associated with administering such a booster dose.

“If I had received AstraZeneca in the first dose and Pfizer in the second dose, would I have been able to get the modern vaccine in the third dose? Will this be a problem for future trips abroad?”

On several occasions in recent weeks, Quebec and Canadian public health officials have asked vaccinated people not to turn their noses at the vaccine maker given the booster dose. Often, those who received the Pfizer vaccine refused to receive the modern vaccine.

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Experts say the two mRNA vaccines are identical. Statistical estimates, however, show that those under 30 have a slightly higher risk of myocarditis or pericarditis (very rare) with moderna – which is why Pfizer vaccine is preferred for 18-29 year olds.

Around the world, vaccines for Pfizer and Moderna are approved by health officials. In the United States, the exchange of these two booster dose vaccines has been allowed since last fall. Note that a vaccination schedule linking the dosages of Astrogenogen and MRNA vaccines is also approved in the United States.

“How long do I have to wait to get the vaccine dose after an infection? ⁇

The answer will depend on who you ask … On January 12, the MSSS called on people who had been double-vaccinated and those with Covit-19 to receive a third dose once they had recovered. The government has already announced that three doses of the vaccine will be needed “soon” to make the vaccine passport valid, although it does not specify a date for the measure to take effect.

Until now, it has been recommended to wait three months or at least eight weeks before vaccinating after infection. The new instruction simplifies the message about eligibility for the booster dose: if the last dose is more than three months old, it is time to get a new one even if you are suffering from the disease. It is often difficult to confirm Govt-19 infection, especially with some recent tests.

The same news is being broadcast in other provinces. In Ontario, eligibility for a booster dose does not take into account infection. In British Columbia, you are asked to wait 10 days after the onset of symptoms before receiving the booster dose.

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Government recommendations vary, but D’s analysisR. Gaston de Ceres, medical consultant at the National Institutes of Public Health in Quebec, is no exception. “If you have an Omigran infection, you run the risk of getting it next week,” he says. In fact, the Quebec Committee on Immunization has not changed its recommendation for at least eight weeks between an infection and a booster dose.

This recommendation is based on the fact that the infection already raises the level of antibodies, and in this situation, the short-term dose of the vaccine is somewhat ineffective. Can a booster dose increase the risk of side effects immediately after infection? “We have little data,” says DR. From Ceres. “Generally, more side effects occur when a person with an infectious disease receives the dose of the vaccine. But it is not clear if there is a big difference if he gets that dose four or eight weeks after the infection. ⁇